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Anti-RIPK1 antibody produced in chicken
产品编号: | 3391894 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-RIPK1 antibody produced in chicken
Anti-RIP
Anti-Receptor-interacting serine/threonine-protein kinase 1
基本信息
MDL number | MFCD01633826 |
NACRES | NA.41 |
Immunogen【免疫原】 | Recombinant receptor (TNFRSF)-interacting serine-threonine kinase 1 Immunogen Sequence: GI # 4506539, sequence 337-525 |
Application【应用】 | Anti-RIPK1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. |
Biochem/physiol Actions【生化/生理作用】 | Receptor-interacting serine/threonine-protein kinase 1 is an enzyme encoded by RIPK1 gene in humans. It is a multifunctional protein containing an N-terminal Ser/Thr kinase and a C-terminal death domain. RIPK1 acts as a key regulatory molecule involved in regulating both cell death and cell survival. It plays an important role in regulating multiple cellular mechanisms, its dynamic regulation, the physiological and pathological roles of RIP1 kinase in human health and disease. RIP1 is an essential upstream signaling molecule in tumor-necrosis-factor-α-induced necroptosis. It is a novel form of apoptosis-inducing protein and participates in the TNF signaling cascades leading to apoptosis and NF-κB activation. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
biological source【生物来源】 | chicken |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
manufacturer/tradename | Genway 15-288-21168 |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_003795.1 |
UniProt accession no.【UniProt登记号】 | Q13546 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... RIPK1(8737) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |