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Anti-PYCARD antibody produced in rabbit
基本信息
| MDL number | MFCD03096627 |
| General description【一般描述】 | Apoptosis-associated speck-like protein containing a CARD (Pycard) is a member of a superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspases. It is found in the cytoplasm but following apoptosis it is found localized near the nucleus in ball like structures. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of mouse PYCARD |
| Application【应用】 | HS5 myeloid cell lysates were subjected to western blot analysis where blots were probed with rabbit anti-pycard at a 1:1000 dilution. |
| Biochem/physiol Actions【生化/生理作用】 | Pycard is a cytosolic soluble protein that forms insoluble aggregates and enhances etoposide-induced apoptosis. |
| Sequence【序列】 | Synthetic peptide located within the following region: TVLRDMGLQELAEQLQTTKEESGAVAAAASVPAQSTARTGHFVDQHRQAL |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 21 kDa |
| species reactivity | mouse, human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_075747 |
| UniProt accession no.【UniProt登记号】 | Q9EPB4 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... PYCARD(66824) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
