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Anti-PRKCB1, (N-terminal) antibody produced in rabbit
产品别名
Anti-PRKCB1, (N-terminal) antibody produced in rabbit
Anti-MGC41878
Anti-PRKCB
Anti-PRKCB2
Anti-PKC-β
Anti-PKCB
基本信息
| MDL number | MFCD00282409 |
| NACRES | NA.41 |
| General description【一般描述】 | The PRKCB1 (protein kinase C β) gene encodes for a serine/threonine kinase. The protein consists of a regulatory moiety at its N-terminal, a catalytic domain at C-terminal and a flexible hinge region joining the two. The PRKCB1 gene is located within the human chromosome 16p12.2-p12. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human PRKCB1 |
| Biochem/physiol Actions【生化/生理作用】 | The members of protein kinase C (PKC) family participate in important biological processes such as cell proliferation, differentiation and apoptosis. PKC promotes cancer progression and is therefore prefered as a target for chemotherapy. Activation of PKC β prevents the stimulation of endothelial nitric oxide synthase induced by insulin. Inhibition of PKC β retains vascular function. PKC β action is associated with endothelial inflammation. |
| Sequence【序列】 | Synthetic peptide located within the following region: CFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 77 kDa |
| species reactivity | rat, human, bovine, dog, mouse, guinea pig, rabbit |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NM_002738 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PRKCB1(5579) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
