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Anti-PIWIL1 antibody produced in rabbit
产品别名
Anti-PIWIL1 antibody produced in rabbit
Anti-HIWI
Anti-piwi-like 1
Anti-MIWI
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The PIWI-like protein 1 (PIWIL1) belongs to the Piwi subfamily.gene is mapped to human chromosome 12q24.33. It is expressed in the cytosol of spermatocytes and spermatids. PIWI-like protein 1 (PIWIL1) is also an Argonaute protein family member. |
| Specificity【特异性】 | Anti-PIWIL1 recognizes human and mouse PIWIL1. |
| Application【应用】 | Anti-PIWIL1 antibody produced in rabbit has been used in western blotting and immunohistochemistry. |
| Biochem/physiol Actions【生化/生理作用】 | The PIWI-like protein 1 (PIWIL1) mediates spermatogenesis. Its aberrant expression favors tumor progression inadenocarcinoma. PIWI-like protein 1 (PIWIL1) plays a key role in embryogenesis, differentiation, stem cell proliferation, growth, and development. High levels of PIWIL1 expression is implicated in the colorectal cancer invasion. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~95 kDa |
| species reactivity | mouse, human |
| packaging【包装】 | antibody small pack of 25 μL |
| concentration【浓度】 | ~1.0 mg/mL |
| technique(s) | immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded mouse testis and biotin / ExtrAvidinTM-Peroxidase staining system. western blot: 1-2 μg/mL using lysates of HEK-293Tcells over expressing human PIWIL1. |
| UniProt accession no.【UniProt登记号】 | Q96J94 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PIWIL1(9271) |
产品说明
| Storage and Stability【储存及稳定性】 | Store at –20 ℃. For continuous use, the product may be stored at 2–8 ℃ for up to one month. For extended storage, freeze at –20 ℃ in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
