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Anti-Phospholipase A2 (iPLA2) antibody produced in rabbit

产品编号:3386008
规格:~1.5 mg/mL, affinity isolated antibody
包装规格:200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3386008200 μL5040
产品别名

Anti-Phospholipase A2 (iPLA2) antibody produced in rabbit

Anti-PLA2

Anti-Phospholipase A2, group VI (cytosolic, calcium-independent)

Anti-IPLA2-VIA

Anti-iPLA2

Anti-PLA2G6

Anti-PARK14

Anti-GVI

Anti-PNPLA9

Anti-CaI-PLA2

Anti-INAD1

基本信息
MDL number
MFCD00803786
NACRES
NA.41
General description【一般描述】
Calcium-independent phospholipase A2 (iPLA2) belongs to the group six of phospholipase A2 (PLA2) enzymes. The protein is encoded by the gene mapped to human chromosome 22q13.1. iPLA2 is an intracellular enzyme. It is present both in the cytosol and in membrane fractions. The encoded protein contains 752 amino acids and has a mass of 85kDa. It is characterized with a eight ankyrin repeats and a catalytic domain.
Application【应用】
Anti-Phospholipase A2 (iPLA2) antibody produced in rabbit has been used in western blotting.
Biochem/physiol Actions【生化/生理作用】
Calcium-independent phospholipase A2 (iPLA2) in the absence of Ca2+, catalyzes the hydrolysis of the Sn-2 ester bond in phospholipids to produce free fatty acids and lysophospholipids. iPLA2 might play an essential role in activating the receptor-mediated signaling pathway. Additionally, it also yields precursors for bioactive compounds such as eicosanoid and platelet-activating factor. The encoded protein performs housekeeping role in phospholipid remodeling.
Physical form【外形】
Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
200
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
~85 kDa (and ~95 kDa human iPLA2 and ~95 kDa mouse and rat iPLA2.)
species reactivity
human, mouse, rat
concentration【浓度】
~1.5 mg/mL
technique(s)
western blot: 1.5-3.0 μg/mL using using extracts of HEK-293T cells overexpressing human iPLA2, RAW264 cell lysates and rat pancreas extracts (S1 fraction).
UniProt accession no.【UniProt登记号】
O60733
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... PLA2G6(8398)
mouse ... pla2g6(53357)
rat ... pla2g6(360426)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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