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Anti-phospho-TP53 (pSer315) antibody produced in rabbit
产品别名
Anti-phospho-TP53 (pSer315) antibody produced in rabbit
Anti-LFS1 antibody produced in rabbit
Anti-TRP53 antibody produced in rabbit
Anti-p53 antibody produced in rabbit
Anti-tumor protein p53 antibody produced in rabbit
Anti-FLJ92943 antibody produced in rabbit
基本信息
| MDL number | MFCD00164709 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of serine 315 (S-S-S(p)-P-Q), according to the protein TP53. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~53 kDa |
| species reactivity | human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (S-S-SP-P-Q) |
| NCBI accession no.【NCBI登记号】 | NP_000537.3 |
| UniProt accession no.【UniProt登记号】 | P04637 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TP53(7157) |
产品说明
| Target description【目标描述】 | Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
