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Anti-phospho-TIP60 (pSer86) antibody produced in rabbit
产品别名
Anti-phospho-TIP60 (pSer86) antibody produced in rabbit
Lysine acetyltransferase 5
KAT5
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 58 kDa |
| species reactivity | mouse, rat, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q92993 |
| UniProt accession no.【UniProt登记号】 | Q92993 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... KAT5(10524) |
基本信息
| General description【一般描述】 | The TIP60 (HIV1 (human immunodeficiency virus 1)-TAT interactive protein) gene is mapped to human chromosome 11q13.1. It is ubiquitously expressed and evolutionarily conserved. The encoded protein, Tip60 belongs to the MYST (Moz, Ybf2/Sas3, Sas2 and TIP60) family. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human TIP60 around the phosphorylation site of Ser86. Immunogen Range: 52-101 |
| Application【应用】 | TIP60 (HIV1-TATinteractive protein) possess acetyltransferase activity and participates in chromatin remodeling and DNA damage repair. TIP60 is involved in protein stabilization and protein function modulation. The presence of chromodomain and MYST domain in its structure enables acetylation of both histone and non-histone proteins. TIP60 in association with androgenic receptors and transcription factors can control gene transcription and cell cycle process. TIP60 mediates p53 action to induce apoptosis. TIP60 inhibits Hepatitis B virus infection. TIP60 acts as a haploinsufficient tumor suppressor. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
