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Anti-phospho-Survivin (pThr34) antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Survivin is also termed as BIRC5 (baculoviral inhibitor of apoptosis repeat-containing 5). It is a multifunctional protein. It belongs to the inhibitor of apoptosis protein (IAP) family. BIRC5 is expressed in fetal tissues and several human malignancies like melanoma. Survivin is located on human chromosome 17q25. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Survivin around the phosphorylation site of Thr34. Immunogen Range: 11-60 |
| Biochem/physiol Actions【生化/生理作用】 | Survivin/BIRC5 (baculoviral inhibitor of apoptosis repeat-containing 5) plays a major role in ATL (adult T-cell leukemia/lymphoma) cell viability. It can block apoptosis and induce the multiplication of cell. BIRC5 also plays a major role in the development of cancer. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 16 kDa |
| species reactivity | human, rat, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | O15392 |
| UniProt accession no.【UniProt登记号】 | O15392 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BIRC5(332) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
