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Anti-phospho-Period Circadian Protein 2 (pSer662) antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The PER2 (period circadian regulator 2) gene is mapped to human chromosome 2q37.3. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Period Circadian Protein 2 around the phosphorylation site of Ser662. Immunogen Range: 636-685 |
| Biochem/physiol Actions【生化/生理作用】 | PER2 (period circadian regulator 2) possess a physiological and pathological control over the mammalian circadian clock. Abnormal expression of PER2 gene leads to the development of a variety of cancer. Loss of PER2 gene function is observed in the onset of oral squamous cell carcinoma. PER2 might act as an essential biomarker for the same. The reciprocal negative regulation loop of PER2 modulates hepatic circadian clock and the process of aging. PER2 is associated with the pathogenesis of rheumatoid arthritis. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 136 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | O15055 |
| UniProt accession no.【UniProt登记号】 | O15055 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PER2(8864) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
