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Anti-phospho-PAK1/PAK2/PAK3 (pThr423/pThr402/pThr421) antibody produced in rabbit

产品编号:3385445
规格:affinity isolated antibody
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3385445100 μG5040
产品别名

Anti-phospho-PAK1/PAK2/PAK3 (pThr423/pThr402/pThr421) antibody produced in rabbit

Anti-CDKN1A antibody produced in rabbit

Anti-PAK65 antibody produced in rabbit

Anti-ADE2 antibody produced in rabbit

基本信息
MDL number
MFCD02097133
NACRES
NA.41
Immunogen【免疫原】
Peptide sequence around phosphorylation site of threonine 423 /402/421 (R-S-T(p)-M-V), according to the protein PAK1/PAK2/PAK3.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
产品性质
biological source【生物来源】
rabbit
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
61-67 kDa
68-74 kDa
species reactivity
human, rat, mouse
concentration【浓度】
1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
isotype【同位素/亚型】
IgG
immunogen sequence【免疫原序列】
(R-S-TP-M-V)
NCBI accession no.【NCBI登记号】
NP_001121638.1
NP_001122092.1
NP_002568.2
UniProt accession no.【UniProt登记号】
Q13177
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... PAK1(5058), PAK2(5062), PAK3(5063)
产品说明
Target description【目标描述】
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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