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Anti-Phospho-INSR-pY1185 antibody produced in rabbit

产品编号:3384921
规格:affinity isolated antibody, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3384921100 μG5040
产品别名

Anti-Phospho-INSR-pY1185 antibody produced in rabbit

Anti-Insulin receptor [Precursor]

Anti-CD220 antigen

Anti-INSR

Anti-IR

基本信息
NACRES
NA.41
General description【一般描述】
Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake, thereby mediating the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3′-kinase (PI3K). This protein can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked.
Immunogen【免疫原】
INSR (NP_000199, 1167-1202)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1185 of human INSR.
Physical form【外形】
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
产品性质
biological source【生物来源】
rabbit
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
human
technique(s)
dot blot: suitable
indirect ELISA: 1:1000
NCBI accession no.【NCBI登记号】
NP_000199
UniProt accession no.【UniProt登记号】
P06213
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... INSR(3643)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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