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Anti-phospho-Histone H3.1 (pSer10) antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Mammals contain three main classes of histone H3 variants: the replicative histones (H3.1 and H3.2), the replacement histone (H3.3) and the centromeric histone (Cenp-A). H3.1 is also called as HIST1H3E. It is mainly expressed in the S phase. HIST1H3E is located on human chromosome 6p22. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Histone H3.1 around the phosphorylation site of Ser10. Immunogen Range: 1-50 |
| Biochem/physiol Actions【生化/生理作用】 | Histone proteins are basic building blocks of chromatin. Mutations in histone H3 results in adult cerebellar high-grade gliomas. It controls protein-protein interactions to induce binding of trans-acting factors that drive chromatin condensation. H3.1 acts as a replication-dependent histone. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 15 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P68431 P84243 Q71DI3 |
| UniProt accession no.【UniProt登记号】 | P68431 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... HIST1H3A(8350), HIST1H3B(8358), HIST1H3C(8352), HIST1H3D(8351), HIST1H3E(8353), HIST1H3G(8355), HIST1H3H(8357), HIST1H3I(8354), HIST1H3J(8356), HIST1H4A(8359) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
