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Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit
产品别名
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit
Anti-RPD3 antibody produced in rabbit
Anti-HDACL1 antibody produced in rabbit
Anti-histone deacetylase 8 antibody produced in rabbit
基本信息
MDL number | MFCD02686596 |
NACRES | NA.41 |
Immunogen【免疫原】 | Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V), according to the protein HDAC8. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | ~42 kDa |
species reactivity | human |
concentration【浓度】 | 1 mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (R-A-SP-M-V) |
NCBI accession no.【NCBI登记号】 | NP_001159890.1 |
UniProt accession no.【UniProt登记号】 | Q9BY41 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HDAC8(55869) |
产品说明
Target description【目标描述】 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |