您的位置：首页 > 产品中心 > Anti-phospho-ERK8 (pThr175+Tyr177) antibody produced in rabbit
Anti-phospho-ERK8 (pThr175+Tyr177) antibody produced in rabbit
产品别名
Anti-phospho-ERK8 (pThr175+Tyr177) antibody produced in rabbit
ERK7
MAPK15
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Mitogen-activated protein (MAP) kinase 15 (MAPK15) or extracellular signal-regulated kinase 8 (ERK8) belongs to the MAP kinase family. MAPK15 gene is located on human chromosome 8q24.3. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human ERK8 around the phosphorylation site of Thr175 and Tyr177. Immunogen Range: 141-190 |
| Biochem/physiol Actions【生化/生理作用】 | Extracellular signal-regulated kinase 8 (ERK8)/mitogen-activated protein (MAP) kinase 15 aids in maintaining the integrity of the genome. Anaplastic thyroid carcinoma cells show high expression of MAPK15. It controls telomerase reverse transcriptase (hTERT) mRNA expression to regulate telomerase activity. It is highly essential to control the generation of reactive oxygen species. MAPK15 also plays a role in stabilizing proliferating cell nuclear antigen protein. MAPK15 might be involved in the progression of human cancer. Hence it might act as a candidate as an attractive target for cancer therapy. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 59 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q8TD08 |
| UniProt accession no.【UniProt登记号】 | Q8TD08 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MAPK15(225689) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
