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Anti-phospho-Epidermal Growth Factor Receptor (pTyr845) antibody produced in rabbit

产品编号:3384583
规格:affinity isolated antibody, lyophilized powder
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
338458350 μG4330
产品别名

Anti-phospho-Epidermal Growth Factor Receptor (pTyr845) antibody produced in rabbit

Anti-phospho-EGFR (pTyr845)

基本信息
MDL number
MFCD03845329
Immunogen【免疫原】
purified, synthetic phosphopeptide corresponding to residues surrounding tyrosine 845 of human epidermal growth factor receptor.
Biochem/physiol Actions【生化/生理作用】
EGFR is a transmembrane glycoprotein that binds to the EGF family. It is a pivotal regulator of cell proliferation, growth, differentiation and DNA repair after radiation-induced damage. Mutations in the gene encoding EGFR are associated with a number of malignancies including lung cancer and colorectal cancer. Phosphorylation of Tyr845 is associated with EGFR mutation and serves as a surrogate marker.
Physical form【外形】
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
lyophilized powder
species reactivity
human
technique(s)
flow cytometry: 5 μg/mL
immunohistochemistry: 15 μg/mL
western blot: 0.5 μg/mL
UniProt accession no.【UniProt登记号】
P00533
storage temp.【储存温度】
−20℃
Gene Information
human ... EGFR(1956)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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