Anti-phospho-Epidermal Growth Factor Receptor (pTyr¹⁰⁸⁶) antibody produced in rabbit

MFCD03845326

NA.41

synthetic phosphopeptide derived from the region of EGFR that contains tyrosine 1086.

EGFR is a transmembrane glycoprotein that binds to the EGF family. It is a pivotal regulator of cell proliferation, growth, differentiation and DNA repair after radiation-induced damage. Mutations in the gene encoding EGFR are associated with a number of malignancies including lung cancer and colorectal cancer. Tyr1086 is a minor autophosphorylation site and enables the internalization of the receptor.

Solution in Dulbecco′s phosphate buffered saline without Mg²⁺ and Ca²⁺, pH 7.3 with 50% glycerol, 1 mg/mL BSA (protease and IgG free) and 0.05% sodium azide.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous glycerol solution

antigen ~185 kDa

human, mouse, rat

western blot: 1:1,000

P00533

wet ice

−20℃

human ... EGFR(1956)
mouse ... Egfr(13649)

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