Anti-phospho-EIF2S1 (pSer⁴⁹) antibody produced in rabbit

NA.41

Peptide sequence around phosphorylation site of serine 49 (L-L-S(p)-E-L), according to the protein EIF2S1.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~38 kDa

mouse, human, rat

1 mg/mL

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

IgG

(L-L-SP-E-L)

NP_004085.1

P05198

wet ice

−20℃

human ... EIF2S1(1965)

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

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10 - Combustible liquids

WGK 1