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Anti-phospho-CDK6 (pTyr24) antibody produced in rabbit
产品别名
Anti-phospho-CDK6 (pTyr24) antibody produced in rabbit
Anti-STQTL11 antibody produced in rabbit
Anti-cyclin-dependent kinase 6 antibody produced in rabbit
Anti-PLSTIRE antibody produced in rabbit
Anti-MGC59692 antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | CDK6 (cyclin dependent kinase 6) is a serine/threonine kinase. It is a human PLSTIRE gene product that is located on chromosome 7q21. |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of tyrosine 24 (G-A-Y(p)-G-K), according to the protein CDK6. |
| Biochem/physiol Actions【生化/生理作用】 | CDK6 (cyclin dependent kinase 6) participates in the regulation of cell‐cycle, hence it acts as a target for cancer therapy. Upregulation of CDK6 has been observed in various malignancies like leukemia and lymphomas. In hematopoietic stem cells, CDK6 modulates the exit of quiescence. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~36 kDa |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (G-A-YP-G-K) |
| NCBI accession no.【NCBI登记号】 | NP_001138778.1 |
| UniProt accession no.【UniProt登记号】 | Q00534 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CDK6(1021) |
产品说明
| Target description【目标描述】 | Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
