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Anti-phospho-Cdc25b (pSer149) antibody produced in rabbit
产品别名
Anti-phospho-Cdc25b (pSer149) antibody produced in rabbit
Anti-CDC25B antibody produced in rabbit
Anti-cell division cycle 25 homolog B (S. pombe) antibody produced in rabbit
Anti-AI604853 antibody produced in rabbit
基本信息
MDL number | MFCD01633249 |
Immunogen【免疫原】 | Peptide sequence around phosphorylation site of Serine 149 (F-R-S(p)-L-P).according to the protein Cdc25b. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | ~62 kDa |
species reactivity | mouse |
concentration【浓度】 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (F-R-SP-L-P) |
NCBI accession no.【NCBI登记号】 | NP_001104545.1 |
UniProt accession no.【UniProt登记号】 | P30306 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | mouse ... Cdc25b(12531) |
产品说明
Target description【目标描述】 | Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |