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Anti-phospho-Caspase 3 (pSer150) antibody produced in rabbit
基本信息
NACRES | NA.41 |
General description【一般描述】 | Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3 is an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases. CASP3 is mapped to human chromosome 4q35.1. |
Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Caspase 3 around the phosphorylation site of Ser150. Immunogen Range: 116-165 |
Biochem/physiol Actions【生化/生理作用】 | Caspase-3 (CASP3) can degenerate multiple cellular proteins and results in morphological changes and DNA fragmentation in cells at the time of apoptosis. It participates in the growth stimulation. CASP3 plays a major role in the execution phase of apoptosis. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 31 kDa |
species reactivity | human, rat, mouse |
concentration【浓度】 | ~1 mg/mL |
technique(s) | ELISA: 1:40000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
NCBI accession no.【NCBI登记号】 | P42574 |
UniProt accession no.【UniProt登记号】 | P42574 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CASP3(836) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |