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抗-磷酸化-AURKA (pThr288) 兔抗
Anti-phospho-AURKA (pThr288) antibody produced in rabbit
产品别名
抗-磷酸化-AURKA (pThr288) 兔抗
Anti-phospho-AURKA (pThr288) antibody produced in rabbit
Anti-AURA antibody produced in rabbit
Anti-AIK antibody produced in rabbit
Anti-aurora kinase A antibody produced in rabbit
Anti-ARK1 antibody produced in rabbit
Anti-AURORA2 antibody produced in rabbit
基本信息
| MDL number | MFCD06411780 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of threonine 288 (R-T-T(p)-L-M), according to the protein AURKA. |
| Application【应用】 | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~48 kDa |
| species reactivity | mouse, human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (R-T-TP-L-M) |
| NCBI accession no.【NCBI登记号】 | NP_003591.2 |
| UniProt accession no.【UniProt登记号】 | O14965 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... AURKA(6790) |
产品说明
| Target description【目标描述】 | Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity By similarity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
