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Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer831) antibody produced in rabbit
| 产品编号： | 3384080 |
| 规格： | ~1 mg/mL, affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 150 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer831) antibody produced in rabbit
Anti-phospho-AMPA Glutamate Receptor 1 (pSer831)
基本信息
| MDL number | MFCD04040522 |
| NACRES | NA.41 |
| General description【一般描述】 | GluR1 subunits of AMPA receptors are membrane proteins that regulate synaptic plasticity of the central nervous system. This receptor has also been implicated in spatial memory retention. Phosphorylation of serine 831 in GluR1 subunit of the AMPA receptor modulates long-term potentiation in neuronal synapses. Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer831) antibody is specific for the GluR1 subunit (phosphorylated on serine 831) of the AMPA receptor in rats and humans. AMPA is a transmembrane receptor for glutamate that regulates synapsis in the central nervous system. It is composed of 4 types of subunits, GluR1, 2, 3, 4. |
| Immunogen【免疫原】 | synthetic phosphopeptide corresponding to a region near serine 831 of rat glutamate receptor subunit GluR1. The GluR1 sequence is conserved among species and has partial homology to VGLUT2. |
| Application【应用】 | Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer831) antibody is suitable for use in direct ELISA, immunohistochemistry, immunoblot and immunoprecipitation. The antibody may also be used for western blot (1:1,000 using rat hippocampal homogenate). |
| Physical form【外形】 | Solution in 10 mM HEPES buffer, pH 7.5, containing 150 mM NaCl, 100 μg/ml BSA and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 100 kDa |
| species reactivity | rat, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | direct ELISA: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: 1:1,000 using rat brain (hippocampal) homogenate |
| UniProt accession no.【UniProt登记号】 | P42261 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GRIA1(2890) rat ... Gria1(50592) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
