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抗-磷酸化-ABL1/ABL2 (pTyr393/429) 兔抗
Anti-phospho-ABL1/ABL2 (pTyr393/429) antibody produced in rabbit
产品别名
抗-磷酸化-ABL1/ABL2 (pTyr393/429) 兔抗
Anti-phospho-ABL1/ABL2 (pTyr393/429) antibody produced in rabbit
Anti-ARG antibody produced in rabbit
Anti-ABL antibody produced in rabbit
Anti-JTK7 antibody produced in rabbit
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Anti-ABLL antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of tyrosine 393/429 (D-T-Y(p)-T-A), according to the protein ABL1/ABL2. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~210 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (D-T-YP-T-A) |
| NCBI accession no.【NCBI登记号】 | NP_001129472.1 NP_005148.2 |
| UniProt accession no.【UniProt登记号】 | P42684 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ABL1(25), ABL2(27) |
产品说明
| Target description【目标描述】 | Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
