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Anti-PHLPP2 (N-term) antibody produced in rabbit

产品编号:3383997
规格:saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3383997100 μG4610
产品别名

Anti-PHLPP2 (N-term) antibody produced in rabbit

Anti-PHLPP-like

Anti-PHLPP2

Anti-PH domain leucine-rich repeat protein phosphatase-like

Anti-KIAA0931

Anti-PHLPPL

基本信息
NACRES
NA.41
General description【一般描述】
The PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) gene with 18 exons, is mapped to human chromosome 16q22.2. The encoded protein is a isoform of PHLPP family and is composed of 1323 amino acids. PHLPP2 is characterized with a pleckstrin homology domain (PH domain), leucine-rich repeats, a protein phosphatase 2C (PP2C) domain and a PDZ-binding motif.
Immunogen【免疫原】
PHLPP2 (NP_055835, 9-42)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human PHLPP2.
Application【应用】
Anti-PHLPP2 (N-term) antibody produced in rabbit has been used in immunoblotting.
Biochem/physiol Actions【生化/生理作用】
PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) is a tumor suppressor. It plays a vital role in cell survival by inactivating Akt, inhibiting cell-cycle progression and stimulating apoptosis. Expression of PHLPP protein is decreased in hypopharyngeal squamous cell carcinomas (HSCCs). Thus, this protein can be used as a marker to determine the poor prognosis in HSCCs patients.
Physical form【外形】
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
saturated ammonium sulfate (SAS) precipitated
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
NCBI accession no.【NCBI登记号】
NP_055835
UniProt accession no.【UniProt登记号】
Q6ZVD8
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... PHLPP2(23035)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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