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Anti-PARP (Cleaved-Asp214) antibody produced in rabbit
产品别名
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit
ADP-ribosyltransferase 1
ADPRT1
ADPRT
pADPRT-1
PARP
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-PARP (Cleaved-Asp214) Antibody detects endogenous levels of fragment of activated PARP (Cleaved-Asp214) protein. PARP1 (poly (ADP-ribose) polymerase 1) is a nuclear protein that consists of three functional domains. It belongs to the PARP family. It is located on chromosome 1q42. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human PARP. Immunogen Range: 165-214 |
| Application【应用】 | Anti-PARP (Cleaved-Asp214) antibody has been used in Western Blotting. |
| Biochem/physiol Actions【生化/生理作用】 | PARP1 (poly (ADP-ribose) polymerase 1) participates in DNA repair. It serves as a facilitator of homologous recombination. It controls transcription by regulating chromatin structure, altering DNA methylation patterns, acting as a co-regulator of transcription factors and interacting with chromatin insulators. It also plays an important role in the protection of cardiovascular system. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 24 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P09874 |
| UniProt accession no.【UniProt登记号】 | P09874 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PARP1(142) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
