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Anti-Pael-R (GPR37) (N-term) antibody produced in rabbit
产品编号: | 3382210 |
规格: | saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Pael-R (GPR37) (N-term) antibody produced in rabbit
Anti-Endothelin B receptor-like protein-1
endothelin receptor type B-like
Anti-PAELR
Parkin-associated endothelin receptor-like receptor
Anti-ETBR-LP-1
基本信息
NACRES | NA.41 |
General description【一般描述】 | Parkinson is the second most common neurodegenerative disease after Alzheimer′s. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity. |
Immunogen【免疫原】 | PAEL-R (NP_005293.1, 102-136) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide in the N-terminal region of human Pael-R (GPR37). |
Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | saturated ammonium sulfate (SAS) precipitated |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
technique(s) | immunohistochemistry: 1:50-1:100 indirect ELISA: 1:1000 western blot: 1:100-1:500 |
NCBI accession no.【NCBI登记号】 | NP_005293.1 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... GPR37(2861) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |