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Anti-Osteoprotegerin antibody produced in goat
产品别名
Anti-Osteoprotegerin antibody produced in goat
Anti-OPG
基本信息
MDL number | MFCD02097104 |
NACRES | NA.41 |
General description【一般描述】 | The antibody will neutralize the biological activity of recombinant human OPG. The antibody shows 50% cross-reactivity with recombinant mouse OPG. |
Immunogen【免疫原】 | recombinant human OPG expressed in the insect cell line Sf 21. |
Biochem/physiol Actions【生化/生理作用】 | Osteoprotegerin (OPG) secreted by osteoblasts and osteogenis stromal stem cells belongs to the TNF receptor superfamily. OPG is expressed in bone marrow, osteoblasts, heart, lung, kidney, thymus, B lymphocytes, chondrocytes and smooth muscle cells. The ratio of OPG and receptor activator of NF-κB Ligand (RANKL) is crucial for determining the bone mass. Excess levels of OPG lead to osteopetrosis while deficiency results in osteoporosis. |
Physical form【外形】 | Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates. |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | human |
technique(s) | western blot: 0.1-0.2 μg/mL |
UniProt accession no.【UniProt登记号】 | O00300 |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TNFRSF11B(4982) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |