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Anti-Osteopontin antibody produced in goat

产品编号:3381749
规格:affinity isolated antibody, lyophilized powder
包装规格:0.1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
33817490.1 MG4730
产品别名

Anti-Osteopontin antibody produced in goat

Anti-OPN

基本信息
MDL number
MFCD02263865
NACRES
NA.41
General description【一般描述】
The OPN (osteopontin) gene is mapped to mouse chromosome 5 E5 and codes for secreted phosphoprotein 1 and is mostly expressed in bone tissue.
Immunogen【免疫原】
purified recombinant mouse osteopontin expressed in NSO cells.
Biochem/physiol Actions【生化/生理作用】
Osteopontin (OPN) serves as a ligand to a number of integrin receptors which are associated with cell motility, chemotaxis, invasion and cell survival. Upregulation of OPN gene is observed in tumors such as colorectal carcinomas, breast cancer and contributes to its pathogenesis. OPN is associated with obesity by mediating adipocyte inflammation and insulin resistance upon macrophage activation. OPN functions as an effector molecule in extracellular signalling and promotes fibrosis and myocyte growth.
Physical form【外形】
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Analysis Note【分析说明】
Neutralizes the biological activity of recombinant mouse osteopontin using 293 cells.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
goat
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
lyophilized powder
species reactivity
mouse
technique(s)
capture ELISA: 0.2-0.8 μg/mL
immunohistochemistry: 5-15 μg/mL using mouse thymus tissue sections
neutralization: 1-3 μg/mL
western blot: 0.1-0.2 μg/mL
UniProt accession no.【UniProt登记号】
P10923
storage temp.【储存温度】
−20℃
Gene Information
mouse ... Spp1(20750)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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