您的位置:首页 > 产品中心 > Anti-Orai1 兔抗
Anti-Orai1 兔抗
Anti-ORAI1 antibody produced in rabbit
产品编号: | 3381632 |
规格: | ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution |
包装规格: | 200 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Orai1 兔抗
Anti-ORAI1 antibody produced in rabbit
Anti-CRACM1
Anti-Calcium release-activated calcium channel protein 1
Anti-TMEM142A
Anti-Transmembrane protein 142A
TMEM142A
CRACM1
基本信息
NACRES | NA.41 |
General description【一般描述】 | ORAI calcium release-activated calcium modulator 1 (ORAI1) is the pore-forming subunit of the Ca2+ release-activated (CRAC) channel. The protein possesses four predicted transmembrane domains and intracellular amino and carboxyl-terminal domains. The ORAI1 gene is localized on human chromosome 12q24.31. |
Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 288-301 of human ORAI1, conjugated to KLH. The corresponding sequence differs by 2 amino acids in rat and mouse. |
Application【应用】 | Anti-ORAI1 antibody produced in rabbit has been used in immunohistochemistry and Western blotting. |
Biochem/physiol Actions【生化/生理作用】 | ORAI calcium release-activated calcium modulator 1 (ORAI1) modulates Ca2+ entry into cells. The channel is activated by stromal interaction molecule-1 (STIM-1). Mutation in the gene encoding the protein has been linked to late-onset tubular aggregate myopathy and congenital miosis. |
Physical form【外形】 | 0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。 |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~35 kDa (non-glycosylated) antigen ~50 kDa (glycosylated) |
species reactivity | human |
concentration【浓度】 | ~1.0 mg/mL |
technique(s) | western blot: 1-2 μg/mL using whole extract of human HEK-293T cells expressing ORAI1 |
UniProt accession no.【UniProt登记号】 | Q96D31 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... ORAI1(84876) mouse ... Orai1(109305) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |