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Anti-Orai1 兔抗

Anti-ORAI1 antibody produced in rabbit
产品编号:3381632
规格:~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
包装规格:200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3381632200 μL5270
产品别名

Anti-Orai1 兔抗

Anti-ORAI1 antibody produced in rabbit

Anti-CRACM1

Anti-Calcium release-activated calcium channel protein 1

Anti-TMEM142A

Anti-Transmembrane protein 142A

TMEM142A

CRACM1

基本信息
NACRES
NA.41
General description【一般描述】
ORAI calcium release-activated calcium modulator 1 (ORAI1) is the pore-forming subunit of the Ca2+ release-activated (CRAC) channel. The protein possesses four predicted transmembrane domains and intracellular amino and carboxyl-terminal domains. The ORAI1 gene is localized on human chromosome 12q24.31.
Immunogen【免疫原】
synthetic peptide corresponding to amino acids 288-301 of human ORAI1, conjugated to KLH. The corresponding sequence differs by 2 amino acids in rat and mouse.
Application【应用】
Anti-ORAI1 antibody produced in rabbit has been used in immunohistochemistry and Western blotting.
Biochem/physiol Actions【生化/生理作用】
ORAI calcium release-activated calcium modulator 1 (ORAI1) modulates Ca2+ entry into cells. The channel is activated by stromal interaction molecule-1 (STIM-1). Mutation in the gene encoding the protein has been linked to late-onset tubular aggregate myopathy and congenital miosis.
Physical form【外形】
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
200
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen ~35 kDa (non-glycosylated)
antigen ~50 kDa (glycosylated)
species reactivity
human
concentration【浓度】
~1.0 mg/mL
technique(s)
western blot: 1-2 μg/mL using whole extract of human HEK-293T cells expressing ORAI1
UniProt accession no.【UniProt登记号】
Q96D31
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... ORAI1(84876)
mouse ... Orai1(109305)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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