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Anti-OPRM1 (Ab-375) antibody produced in rabbit
产品别名
Anti-OPRM1 (Ab-375) antibody produced in rabbit
Anti-MOR1 antibody produced in rabbit
Anti-KIAA0403 antibody produced in rabbit
Anti-MOR antibody produced in rabbit
Anti-OPRM antibody produced in rabbit
Anti-opioid receptor, mu 1 antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The gene OPRM1 (opioid receptor μ 1) is mapped to human chromosome 6q24-q25. The gene spans a length of 200kb and contains 11 exons that yield 17 splice variants. |
| Immunogen【免疫原】 | Peptide sequence around aa. 373-377 (H-P-S-T-A), according to the protein OPRM1. |
| Application【应用】 | Anti-OPRM1 (Ab-375) antibody produced in rabbit has been used in Western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | The gene OPRM1 (opioid receptor μ 1) encodes a μ opioid receptor that functions in pain perception and addiction to drugs of abuse, such as cocaine, nicotine and alcohol. It serves as a target for opioid drugs, such as morphine, methadone and heroin and opioid peptides (like β - endorphin and endomorphins) and mediates their effects. Single nucleotide polymorphism in the OPRM1 gene is associated with an inclination to drug addiction and lesser response to painful stimuli. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~80 kDa |
| species reactivity | rat, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (H-P-S-T-A) |
| NCBI accession no.【NCBI登记号】 | NP_000905.3 |
| UniProt accession no.【UniProt登记号】 | P42866 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... OPRM1(4988) |
产品说明
| Target description【目标描述】 | Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
