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Anti-Op18 (ab2) antibody produced in rabbit
| 产品编号： | 3381006 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Op18 (ab2) antibody produced in rabbit
Anti-LAP18
Anti-Stathmin 1
Anti-STMN1
Anti-Oncoprotein 18
Anti-Lag
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human, mouse, rat |
| technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | P16949 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... STMN1(3925) |
基本信息
| General description【一般描述】 | Op18 (oncoprotein 18) is a cytoplasmic phosphoprotein, that is of 17kDa. It is also termed as stathmin1 (STMN1). It is partially found in the nucleus of all tumor tissues. It is located on chromosome 1p36.1. |
| Immunogen【免疫原】 | a 17 amino acid peptide from near the amino-terminus of human op18. |
| Biochem/physiol Actions【生化/生理作用】 | Op18 (oncoprotein 18) plays a major role in the multiplication and migration of hypopharyngeal squamous cell carcinoma (HSCC), hence it can be considered as a therapeutic target of HSCC. It participates in the reconstitution of microtubule cytoskeleton, cell cycle progression and cell migration. Silencing STMN1 may affect the cell cycle progression, apoptosis, metastasis and chemoresistance of tumor cells. |
| Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP4237. |
| Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
