Anti-OLIG2 (AB1) antibody produced in rabbit

NA.41

Oligodendrocyte lineage transcription factor 2 (OLIG2), a basic helix-loop-helix transcription factor, is an essential regulator of ventral neuroectodermal progenitor cell fate and is required for oligodendrocyte and motor neuron development. OLIG2 is a universal marker of diffuse gliomas including oligodendroglioma, astrocytoma, glioblastoma, and mixed glioma.
Rabbit polyclonal anti-OLIG2 antibody reacts with chicken, human, and mouse oligodendrocyte lineage transcription factor 2 transcription factors.

Synthetic peptide directed towards the C-terminal region of Human OLIG2

Rabbit polyclonal anti-OLIG2 antibody is used to tag oligodendrocyte lineage transcription factor 2 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of oligodendrocyte lineage transcription factor 2 in ventral neuroectodermal progenitor cell fate and as a diffuse glioma marker protein.
Rabbit Anti-OLIG2 (AB1) antibody can be used for western blot applications at a concentration of 0.5 μg/ml.

OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14;21)(q11.2;q22). OLIG2 might play a role in learning deficits associated with Down syndrome.

Synthetic peptide located within the following region: AAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGF

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

32 kDa

human

0.5 mg - 1 mg/mL

immunohistochemistry: suitable
western blot: suitable

NP_005797

Q13516

wet ice

−20℃

human ... OLIG2(10215)

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12 - Non Combustible Liquids

WGK 3