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Anti-NDRG1 (AB2) antibody produced in rabbit
产品别名
Anti-NDRG1 (AB2) antibody produced in rabbit
Anti-NDR1
Anti-NMSL
Anti-N-myc downstream regulated gene 1
Anti-HMSNL
Anti-CAP43
Anti-GC4
Anti-DRG1
Anti-CMT4D
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | N-myc downstream regulated 1 (NDRG1) is a cytoplasmic hydrolase that modulates stress, hormonal responses, cell growth, differentiation and LDL receptor trafficking. It mediates antimetastatic effects in cancer cells and is downregulated in prostate cancer cells. Rabbit Anti-NDRG1 antibody recognizes canine, human, mouse, rat, chicken, and bovine NDRG1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human NDRG1 |
| Application【应用】 | Rabbit Anti-NDRG1 antibody is suitable for western blot applications at a concentration of 2.5μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | NDRG1 is a member of the N-myc downregulated protein family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in its gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. |
| Sequence【序列】 | Synthetic peptide located within the following region: MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCG |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 43 kDa |
| species reactivity | rat, human, pig, rabbit, horse, mouse, bovine |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001128714 |
| UniProt accession no.【UniProt登记号】 | Q92597 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NDRG1(10397) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
