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Anti-MLK3 antibody produced in rabbit
产品别名
Anti-MLK3 antibody produced in rabbit
MAP3K11
mitogen activated protein kinase kinase kinase 11
kinase MLK3
M3K11
MAPKKK11
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Mitogen-activated protein kinase kinase kinase 11 (MAP3K11) or mixed lineage kinase 3 (MLK3) possesses an amino-terminal Src-homology-3 (SH3) domain followed by a kinase domain, a leucine-zipper region, a Cdc42/RAC interacting motif (CRIB) and a carboxy terminal proline/serine/threonine-rich domain. The gene encoding this serine/threonine protein kinase is localized on human chromosome 11q13.1. Anti-MLK3 Antibody detects endogenous levels of total MLK3 protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human MLK3. Immunogen Range: 640-689 |
| Biochem/physiol Actions【生化/生理作用】 | Mitogen-activated protein kinase kinase kinase 11 (MAP3K11), also known as mixed lineage kinase 3 (MLK3), phosphorylates c-Jun N-terminal kinases. It acts as a modulator of the mitogen-activated protein kinase (MAPK) pathway. The protein is associated with various cancers. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 92 kDa |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 |
| NCBI accession no.【NCBI登记号】 | Q16584 |
| UniProt accession no.【UniProt登记号】 | Q16584 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MAP3K11(4296) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
