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Anti-MFNG (AB2) antibody produced in rabbit

产品编号:3376409
规格:affinity isolated antibody
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3376409100 μL6250
产品别名

Anti-MFNG (AB2) antibody produced in rabbit

Anti-MFNG O-fucosylpeptide 3-β-N-acetylglucosaminyltransferase

基本信息
NACRES
NA.41
General description【一般描述】
MFNG codes for a secretory protein that plays a role in Notch signaling during embryonic development. This secretory protein exhibits fucose-specific β-1,3-N-acetylglucosaminyltransferase functions which can lead to the elongation of O-linked fucose residues in Notch.
Rabbit Anti-MFNG antibody recognizes bovine, human, mouse, rat, and canine MFNG.
Immunogen【免疫原】
Synthetic peptide directed towards the C terminal region of human MFNG
Application【应用】
Rabbit Anti-MFNG antibody is suitable for western blot applications at a concentration of 0.25 μg/ml.
Biochem/physiol Actions【生化/生理作用】
MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Sequence【序列】
Synthetic peptide located within the following region: QLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYP
Physical form【外形】
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
36 kDa
species reactivity
horse, dog, rat, rabbit, human
concentration【浓度】
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_002396
UniProt accession no.【UniProt登记号】
O00587
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... MFNG(4242)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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