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Anti-MAT1 antibody produced in rabbit
产品别名
Anti-MAT1 antibody produced in rabbit
MAT-I/III
MATA1
AMS1
AdoMet synthetase
基本信息
MDL number | MFCD00211613 |
NACRES | NA.41 |
General description【一般描述】 | Anti-MAT1 Antibody detects endogenous levels of total MAT1 protein. CDK activating kinase assembly factor MNAT1 or MAT1 enzyme is encoded by the MNAT1 gene in humans and is localized to chromosome 14q23. The protein is part of the cyclin-dependent kinase-activating kinase complex. |
Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human MAT1. Immunogen Range: 91-140 |
Biochem/physiol Actions【生化/生理作用】 | CDK activating kinase assembly factor MNAT1 or MAT1 is functionally associated with the general transcription/DNA repair factor TFIIH. It is an assembly factor that targets subunits of both cyclin-dependent kinase-activating kinase (CAK) and TFIIH kinase. MAT1 regulates cell cycle and transcription. This protein associates with cyclin H and cyclin-dependent kinase 7 (CDK7) and forms the CDK-activating kinase (CAK) complex. The complex activates several cyclin-associated kinases, regulates cell cycle progression and activates RNA polymerase II-mediated transcription. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 35 kDa |
species reactivity | rat, human, mouse |
concentration【浓度】 | ~1 mg/mL |
technique(s) | ELISA: 1:20000 western blot: 1:500-1:1000 |
NCBI accession no.【NCBI登记号】 | P51948 |
UniProt accession no.【UniProt登记号】 | P51948 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MNAT1(4331) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |