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Anti-INOS antibody produced in rabbit
产品别名
Anti-INOS antibody produced in rabbit
NITRIC OXIDE SYNTHASE
INDUCIBLE
inducible NOS
Hepatocyte NOS
HEP-NOS
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The INOS (inducible nitric oxide synthase) gene is mapped to human chromosome 17q11.2. Anti-INOS antibody detects endogenous levels of total INOS protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human iNOS. Immunogen Range: 117-166 |
| Application【应用】 | Anti-INOS, N-Terminal antibody produced in rabbit has been used in western blotting and immunohistochemistry. Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper) |
| Biochem/physiol Actions【生化/生理作用】 | Upregulation of INOS (inducible nitric oxide synthase) is observed during infections, tissue injury, and inflammation. INOS is responsible to produce NO (nitric oxide), which controls blood flow by inducing vascular relaxation. NO acts as a neurotransmitter and can facilitate immune responses. NO can also bring about anti-thrombotic and anti-inflammatory effects in response to oxidative stress, hypoxia, inflammatory cytokines (TNF-α, IL-1β, IFN-γ), and lipopolysaccharide endotoxin. iNOS generates more NO than the neuronal and endothelial NOS. Unlike the two isoforms, iNOS is calcium independent. INOS might be associated with type 2 diabetes mellitus. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 131 kDa |
| species reactivity | human, rat, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P35228 |
| UniProt accession no.【UniProt登记号】 | P35228 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NOS2(4843) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
