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Anti-IL-37 antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | IL-37 (interleukin 37) is an anti-inflammatory cytokine and is also termed as IL-1 family member 7 (IL-1F7). IL-37 belongs to the IL-1 cytokine family. This protein is expressed in blood monocytes, endothelial cells, adipocytes and epithelial cells. IL-37 is located on human chromosome 2q12. |
| Immunogen【免疫原】 | Antibody was raised against a 17 amino acid peptide near the amino terminus of human IL-37. |
| Biochem/physiol Actions【生化/生理作用】 | IL-37 (interleukin 37) acts as a suppressor for innate immunity and acquired immunity. IL-37 participates in the immunosuppressive property of human CD4+CD25+ regulatory T cells. It represses the synthesis of several pro-inflammatory cytokines like IL-1α, IL-1β, IL-6, IL-12, granulocyte colony-stimulating factor (G-SCF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and TNF-α (tumor necrosis factor alpha). It plays an important role in adaptive immunity. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500952. |
| Physical form【外形】 | Supplied at 1 mg/mL in PBS with 0.02% sodim azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | predicted mol wt 24 kDa |
| species reactivity | human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | ELISA: suitable immunoblotting: suitable immunofluorescence: suitable immunohistochemistry: suitable |
| NCBI accession no.【NCBI登记号】 | NP_055254 |
| UniProt accession no.【UniProt登记号】 | Q9NZH6 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL37(27178) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
