Anti-IKAP antibody produced in rabbit

MFCD04118553

NA.41

IKAP (IKK-complex-associated protein) is considered as a subunit of the RNA Pol II elongator complex. It is also known as IKBKAP (Ikappakinase complex-associated protein or human elongator factor 1) and ELP1 (elongator protein-1). It has 37 exons and codes for 1332 amino acid IKAP protein, that is of ~150KD. It is present in most of the tissues. It is mapped to chromosome 9q31.

a 16 amino acid peptide from near the carboxy-terminus of human IKAP.

Mutations in IKAP cause familial dysautonomia. It helps to conserve the proliferation of neural precursor and blocks its unexpected differentiation into neurons. It plays an important role in cell motility and migration.

The action of this antibody can be blocked using blocking peptide SBP2337.

Solution in phosphate buffered saline containing 0.02% sodium azide

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

predicted mol wt 134-147 kDa

human, mouse

immunocytochemistry: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable

O95163

dry ice

−20℃

human ... IKBKAP(8518)

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