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ANTI-IDDM12(N-TERMINAL) antibody produced in rabbit
| 产品编号： | 3369072 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 400 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
ANTI-IDDM12(N-TERMINAL) antibody produced in rabbit
Cytotoxic T-lymphocyte protein 4
CD_antigen=CD152
Cytotoxic T-lymphocyte-associated antigen 4
CD152
CTLA4
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | CTLA4 (cytotoxic T-lymphocyte associated protein 4), also known as IDDM12 or CD152 (cluster of differentiation), is a T cell receptor which belongs to the immunoglobulin (Ig) superfamily. It is expressed on the surface of T helper cells. This gene is localized to human chromosome 2q33. This protein is composed of a cytosolic domain, a transmembrane region and a V domain of 116 amino acids. Alternative splicing of IDDM12 results in membrane and soluble forms. The membrane form works as homodimers and the soluble isoforms work as monomers. |
| Biochem/physiol Actions【生化/生理作用】 | CTLA4 (cytotoxic T-lymphocyte associated protein 4) or insulin dependent diabetes mellitus 12 (IDDM12) is responsible for inhibiting T-cell proliferation and facilitates T cell apoptosis. This protein is expressed post-antigen presentation and thus, is involved in immune and autoimmune disorders. It is implicated in the pathogenesis of various T cell mediated autoimmune disorders. |
| Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 24656 Da |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:50-1:100 western blot: 1:2000 |
| NCBI accession no.【NCBI登记号】 | NP_001032720.1 |
| UniProt accession no.【UniProt登记号】 | P16410 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CTLA4(1493) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
