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Anti-HSPB1 (AB2) antibody produced in rabbit
产品别名
Anti-HSPB1 (AB2) antibody produced in rabbit
Anti-Hsp25
Anti-HS.76067
Anti-HSP27
Anti-CMT2F
Anti-HSP28
Anti-Heat shock 27 kDa protein 1
Anti-DKFZp586P1322
基本信息
NACRES | NA.41 |
General description【一般描述】 | HSPB1 is a small, ubiquitous heat shock protein that is involved in regulating cellular apoptosis. Studies have reported that downregulation of HSPB1 (Hsp27) in breast cancer cells can cause the upregulation of PTEN. Rabbit Anti-HSPB1 (AB2) antibody binds to human HSPB1. |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human HSPB1 |
Application【应用】 | Rabbit Anti-HSPB1 (AB2) antibody can be used for western blot (1.25μg/ml) and immunohistochemistry (4-8μg/ml, using paraffin-embedded tissues) assays. |
Biochem/physiol Actions【生化/生理作用】 | HSPB1, like the other heat shock proteins, is part of a complex system of molecular chaperones in epidermal keratinocytes. |
Sequence【序列】 | Synthetic peptide located within the following region: SLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 23 kDa |
species reactivity | human |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001531 |
UniProt accession no.【UniProt登记号】 | P04792 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HSPB1(3315) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |