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Anti-HOXB6 antibody produced in rabbit
产品别名
Anti-HOXB6 antibody produced in rabbit
Anti-Homeobox B6
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 25 kDa |
| species reactivity | human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_061825 |
| UniProt accession no.【UniProt登记号】 | P17509 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... HOXB6(3216) |
基本信息
| General description【一般描述】 | HOXB6 belongs to the HOX family of homeobox protein that regulate hematopoiesis. Overexpression of HOXB6 has been linked to acute myeloid leukemia. Furthermore, HOXB6 is known to interact with CREB-binding protein (CBP) and repress globin expression. Rabbit Anti-HOXB6 antibody recognizes human, mouse, rat, canine, and bovine HOXB6. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human HOXB6 |
| Application【应用】 | Rabbit Anti-HOXB6 antibody can be used for western blot (1μg/ml) applications. |
| Biochem/physiol Actions【生化/生理作用】 | HOXB6 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. |
| Sequence【序列】 | Synthetic peptide located within the following region: ALSGADEQPPFHPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMNSCN |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
