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Anti-HLA-DP alpha 1 antibody, Rabbit monoclonal
| 产品编号： | 3367746 |
| 规格： | clone SP228, recombinant, expressed in proprietary host, affinity isolated antibody |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1) is a class II heterodimer comprising of a polymorphic β and an oligomorphic α chain. It is encoded by the gene mapped to human chromosome 6p21.33. HLA-DPA1 is generally expressed on a subset of Kupffer cells and resident macrophages in liver. HLA-DP is an antigen receptor and one of the MHC class II proteins. HLA-DP is a heterodimer of an alpha and a beta chain. Both chains are type I transmembrane proteins with short cytoplasmic domains. It is expressed on antigen-presenting cells and a variety of other cell types, and is also expressed by various tumors such as melanoma, gastric carcinoma, breast carcinoma, ovarian carcinoma, and lymphoma. |
| Immunogen【免疫原】 | Synthetic peptide derived from human HLA-DP alpha1 protein. |
| Application【应用】 | Anti-HLA-DP alpha 1 antibody, Rabbit monoclonal has been used in immunohistochemistry. |
| Biochem/physiol Actions【生化/生理作用】 | Major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1) alloreactivity is highly relevant in clinical transplantation. It plays an essential role in the presentation of viral antigens to CD4+ T helper (Th) lymphocytes. Studies have suggested that SNP (single nucleotide polymorphisms) of HLA-DP can result in chronic hepatitis B virus (HBV) infection. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | 0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| recombinant【重组】 | expressed in proprietary host |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | SP228, monoclonal |
| species reactivity | human (tested) |
| technique(s) | flow cytometry: 1:100 immunohistochemistry: 1:100 |
| isotype【同位素/亚型】 | IgG |
| UniProt accession no.【UniProt登记号】 | P20036 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | human ... HLA-DPA1(3113) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
