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Anti-HIRA (center) antibody produced in rabbit
产品编号: | 3367532 |
规格: | saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-HIRA (center) antibody produced in rabbit
Anti-TUPLE1
Anti-TUP1-like enhancer of split protein 1
Anti-DGCR1
Anti-HIR
基本信息
NACRES | NA.41 |
General description【一般描述】 | HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. |
Immunogen【免疫原】 | HIRA (NP_003316, 436-471) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human HIRA. |
Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | saturated ammonium sulfate (SAS) precipitated |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
technique(s) | indirect ELISA: 1:1000 western blot: 1:100-1:500 |
NCBI accession no.【NCBI登记号】 | NP_003316 |
UniProt accession no.【UniProt登记号】 | P54198 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HIRA(7290) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |