Anti-HEY1 antibody produced in rabbit

NA.41

Hairy/enhancer-of-split related with YRPW motif 1 (HEY1, HESR1, HERP2, HRT1, CHF2), a basic helix-loop-helix (bHLH)-type transcription factor/repressor, is a downstream effector of Notch and c-Jun signaling. HEY1/HESR1 is involved in the regulation of cardiovascular, skeletal muscle, osteoblast, osteoclast, chondrocyte and neural development. HEY1/HESR1 is a repressor of myoblast differentiation/myogenesis and human dopamine transporter (DAT1) gene expression.

Rabbit polyclonal anti-HEY1/HESR1 antibody reacts with human, mouse, rat, bovine, and canine Hairy/enhancer-of-split related with YRPW motif 1 transcription factors.

Synthetic peptide directed towards the C-terminal region of Human HEY1

Rabbit polyclonal anti-HEY1/HESR1 antibody is used to tag Hairy/enhancer-of-split related with YRPW motif 1 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of Hairy/enhancer-of-split related with YRPW motif 1 in cardiovascular, skeletal muscle, osteoblast, osteoclast, chondrocyte and neural development.

Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. HEY genes are direct transcriptional targets of the Notch signaling pathways in Drosophila and vertebrates.

Synthetic peptide located within the following region: PQNGHGNAGTTASPTEPHHQGRLGSAHPEAPALRAPPSGSFGPVLPVVTS

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

IgG fraction of antiserum

100

primary antibodies

polyclonal

buffered aqueous solution

32 kDa

human

0.5 mg - 1 mg/mL

immunohistochemistry: suitable
western blot: suitable

NP_001035798

Q9Y5J3

wet ice

−20℃

human ... HEY1(23462)

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12 - Non Combustible Liquids

WGK 1