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Anti-Gripap1 antibody produced in rabbit
产品别名
Anti-Gripap1 antibody produced in rabbit
Anti-GRIP1 associated protein 1
Anti-Grasp1
基本信息
NACRES | NA.41 |
General description【一般描述】 | The antibody detects endogenous level of total GRASP protein. |
Immunogen【免疫原】 | Peptide sequence around aa. 814-818 (Q-E-I-V-R ), according to the protein NP_064522.3 |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | ~95 kDa |
species reactivity | human, rat, mouse |
concentration【浓度】 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (Q-E-I-V-R ) |
NCBI accession no.【NCBI登记号】 | NM_020137.3 |
UniProt accession no.【UniProt登记号】 | Q4V328 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | rat ... Gripap1(116493) |
产品说明
Target description【目标描述】 | GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid proteinencoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynapticdensity protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipperregion and a carboxyl-terminal PDZ-binding motif. GRASP is involved withintracellular trafficking and contributes to the macromolecular organizationof group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASPforms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. Italso interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highlyexpressed in brain and has lower levels of expression in lung, heart, embryo,kidney and ovary. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |