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Anti-GATA4 antibody produced in rabbit
产品别名
Anti-GATA4 antibody produced in rabbit
Anti-GATA binding protein 4
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The GATA zinc finger transcription factors are characterized by their ability to bind to the promoter region DNA sequence "GATA" within various genes. GATA4, prevalent in endoderm-derived organs, regulates various genes involved in embryogenesis and in myocardial differentiation and function. |
| Specificity【特异性】 | Anti-GATA4 polyclonal antibody reacts with human, mouse, rat, pig, and canine GATA4 transcription factors. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human GATA4 |
| Application【应用】 | Anti-GATA4 polyclonal antibody is used to tag GATA4 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the possible roles of GATA4 in the regulation of embryogenesis and differentiation primarily within endoderm-derived organs and tissues. |
| Biochem/physiol Actions【生化/生理作用】 | GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. GATA4is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects. |
| Sequence【序列】 | Synthetic peptide located within the following region: MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLG |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 45 kDa |
| species reactivity | human, rat, mouse, rabbit, dog |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_002043 |
| UniProt accession no.【UniProt登记号】 | Q5IFM8 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GATA4(2626) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
