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Anti-FOXO1 (Ab-256) antibody produced in rabbit
产品别名
Anti-FOXO1 (Ab-256) antibody produced in rabbit
Anti-FKH1 antibody produced in rabbit
Anti-FOXO1A antibody produced in rabbit
Anti-forkhead box O1 antibody produced in rabbit
Anti-FKHR antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | FOXO1 (forkhead box O1) is a transcription factor , that belongs to the Foxo subfamily. It is located on human chromosome 13q14. |
| Immunogen【免疫原】 | Peptide sequence around aa. 254-258 (A-A-S-M-D), according to the protein FOXO1. |
| Application【应用】 | Anti-FOXO1 (Ab-256) antibody has been used in immunohistochemistry, immunofluorescence and western blotting . |
| Biochem/physiol Actions【生化/生理作用】 | FOXO1 (forkhead box O1) blocks the differentiation of cell in fetal pancreatic progenitor cells. It controls the differentiation of adipocyte. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 78-82 kDa |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (A-A-S-M-D) |
| NCBI accession no.【NCBI登记号】 | NP_002006.2 |
| UniProt accession no.【UniProt登记号】 | Q12778 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... FOXO1(2308) |
产品说明
| Target description【目标描述】 | FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14 |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
