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Anti-FOXC1 antibody produced in rabbit
产品别名
Anti-FOXC1 antibody produced in rabbit
Anti-Forkhead box C1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | FOXC1 is a forkhead transcription factor that has been implicated in eye development. Variations in FOXC1 have been linked to elevated intraocular pressure and glaucoma. Rabbit Anti-FOXC1 antibody recognizes human and mouse FOXC1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human FOXC1 |
| Application【应用】 | Rabbit Anti-FOXC1 antibody can be used for western blot applications at a concentration of 5.0μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. |
| Sequence【序列】 | Synthetic peptide located within the following region: GERGGHLQGAPGGAGGSAVDNPLPDYSLPPVTSSSSSSLSHGGGGGGGGG |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 57 kDa |
| species reactivity | human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001444 |
| UniProt accession no.【UniProt登记号】 | Q12948 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... FOXC1(2296) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
