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Anti-FN1 antibody produced in rabbit
产品别名
Anti-FN1 antibody produced in rabbit
Anti-DKFZp686O13149
Anti-Fibronectin 1
Fn1 Antibody
Anti-DKFZp686F10164
Anti-FINC
Anti-DKFZp686H0342
Fn1 Antibody-Anti-FN1 antibody produced in rabbit
Anti-FN
Anti-CIG
Anti-DKFZp686I1370
基本信息
NACRES | NA.41 |
General description【一般描述】 | Fibronectins are a class of immunochemically related glycoproteins present in basement membranes, collective tissues and blood wherein they mediate adhesion between matrix components and cells. Plasma fibronectin (CLG) mediates the attachment of monocytes (fibroblasts, macrophages) to various cell matrices and materials such as gelatin. |
Specificity【特异性】 | Anti-FN1 polyclonal antibody reacts with human, canine, rabbit, bovine, rat, and mouse plasma fibronectin (CIG). |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human FN1 |
Application【应用】 | Anti-FN1 polyclonal antibody is used to tag plasma fibronectin (CIG) for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the possible roles of fibronectin (CIG) in the adherence of monocytes to cell matricies and solid surfaces coated with materials such as gelatin. |
Biochem/physiol Actions【生化/生理作用】 | FN1 is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. |
Sequence【序列】 | Synthetic peptide located within the following region: NCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADR |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 76 kDa |
species reactivity | human, bovine, pig, sheep, dog |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_002017 |
UniProt accession no.【UniProt登记号】 | P02751 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... FN1(2335) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |